Found 177 articles for: "melasma"
Combination of In-Office Chemical Peels With a Topical Comprehensive Pigmentation Control Product in Skin of Color Subjects With Facial Hyperpigmentation
April 2017 | Volume 16 | Issue 4 | Original Article | 301 | Copyright © April 2017
Dyschromia is one of the primary complaints for patients with skin of color. Treatments need to achieve a balance between tolerability and efficacy to address existing hyperpigmentation without cau...
Read MoreEfficacy of a Comprehensive Serum in Japanese Subjects With Moderate to Severe Facial Hyperpigmentation
January 2017 | Volume 16 | Issue 1 | Original Article | 36 | Copyright © January 2017
OBJECTIVE: Due to innate differences in the biochemical processes of melanogenesis between people of different ethnic origins, the clinical efficacy and tolerability of a novel comprehensive hydroquin...
Read MoreDevelopment and Clinical Assessment of a Comprehensive Product for Pigmentation Control in Multiple Ethnic Populations
December 2016 | Volume 15 | Issue 12 | Original Article | 1562 | Copyright © December 2016
BACKGROUND: Pigmentary changes in people of different ethnic origins are controlled by slight variations in key biological pathways leading to different outcomes from the same treatment. It is importa...
Read MoreEfficacy of a Skin Condition-Adapted Solution for Xerosis and Itch Relief Associated With Aging
November 2016 | Volume 15 | Issue 11 | Supplement Individual Articles | 91 | Copyright © November 2016
In recent decades, the stratum corneum (SC), has been recognized for its multifunctional role in maintaining the homeostasis of the human epidermal barrier. A better understanding of the SC’s ab...
Read MoreClinical Evaluation of a 4% Hydroquinone + 1% Retinol Treatment Regimen for Improving Melasma and Photodamage in Fitzpatrick Skin Types III-VI
November 2016 | Volume 15 | Issue 11 | Original Article | 1435 | Copyright © November 2016
The benefits of monotherapy with hydroquinone for melasma and retinoids for photodamaged skin ...
Read MoreEvaluation of the Safety and Efficacy of a Low Fluence, Picopulsed, Alexandrite Laser in a Pico-Toning Technique With a Diffractive Lens Optic for the Treatment of Photodamage and Textural Improvement in “Off the Face” Applications
November 2016 | Volume 15 | Issue 11 | Original Article | 1398 | Copyright © November 2016
BACKGROUND: The diffractive optic coupled with a picosecond pulsed alexandrite laser has been shown to effectively minimize pigmen- tation while improving the appearance of textural irregularities and...
Read MoreA Prospective Split-Face Study of the Picosecond Alexandrite Laser With Specialized Lens Array for Facial Photoaging in Chinese
November 2016 | Volume 15 | Issue 11 | Original Article | 1390 | Copyright © November 2016
Background: A 755nm picosecond alexandrite laser with a diffractive lens array has been reported for the treatment of acne scar and photoaging with clinical ef cacy. In this study, we evaluated the ap...
Read MoreTreatment of Facial Photodamage With Mass Market Topical Products vs Non-ablative Fractional Laser
November 2016 | Volume 15 | Issue 11 | Original Article | 1366 | Copyright © November 2016
METHODS: In this split-face, evaluator-blinded study, 18 subjects were randomly assigned to receive either the SSR or NFL treatments on each side of the face. For the SSR facial sides subjects followe...
Read MoreIntegrated Cooling-Vacuum-Assisted Non-Fractional 1540 nm Erbium:Glass Laser is Effective in Treating Acne Scars
November 2016 | Volume 15 | Issue 11 | Original Article | 1359 | Copyright © November 2016
INTRODUCTION: Acne scars are a common result of in ammatory acne, affecting many patients worldwide. Among which, atrophic scars are the most prevalent form, presenting as dermal depressions caused by...
Read MoreA Split-Face Assessment of the Synergistic Potential of Sequential Q-Switched Nd:YAG Laser and 1565 nm Fractional Nonablative Laser Treatment for Facial Rejuvenation in Fitzpatrick Skin Type II-V Patients
November 2016 | Volume 15 | Issue 11 | Original Article | 1335 | Copyright © November 2016
Recent appreciation of the multifactorial pathophysiology of skin aging has led to increased use of parallel treatment regimens. This prospective, split-face, randomized study assessed the safety and ...
Read MoreClinical Trial Review
December 2015 | Volume 14 | Issue 12 | Features | 1488 | Copyright © December 2015
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreAn Evaluation of Efficacy and Tolerability of Novel Enzyme Exfoliation Versus Glycolic Acid in Photodamage Treatment
November 2015 | Volume 14 | Issue 11 | Original Article | 1306 | Copyright © November 2015
BACKGROUND: Glycolic acid acts by chemical destruction of adhesions between skin cells to exfoliate superficial skin layers and excess pigmentation. It is well known to improve the appearance of photo...
Read MoreExpanding the Clinical Application of Fractional Radiofrequency Treatment: Findings on Rhytides, Hyperpigmentation, Rosacea, and Acne Redness
November 2015 | Volume 14 | Issue 11 | Original Article | 1298 | Copyright © November 2015
While radiofrequency has been used medically for decades to treat a wide variety of conditions, its use therapeutically to target conditions affecting the skin is relatively new. With the development ...
Read MoreA Retrospective Study of Patient Satisfaction Following a Trial of Nano-fractional RF Treatment
November 2015 | Volume 14 | Issue 11 | Original Article | 1268 | Copyright © November 2015
Traditional techniques used to treat dermatological conditions have typically involved surgery or full ablation of tissue. With the emergence of fractional radiofrequency (RF) technology, treatment fo...
Read MoreEvaluation of a Low Energy, Low Density, Non-Ablative Fractional 1927nm Wavelength Laser for Facial Skin Resurfacing
November 2015 | Volume 14 | Issue 11 | Original Article | 1262 | Copyright © November 2015
OBJECTIVE: We investigated the safety, tolerability and efficacy of a low energy low density, non-ablative fractional 1,927-nm laser in the treatment of facial photodamage, melasma, and post inflammat...
Read MoreAnalysis of Depth of Ablation, Thermal Damage, Wound Healing, and Wound Contraction With Erbium YAG Laser in a Yorkshire Pig Model
November 2015 | Volume 14 | Issue 11 | Original Article | 1245 | Copyright © November 2015
BACKGROUND AND OBJECTIVES: The erbium YAG laser is commonly used for skin resurfacing. It is known that varying the pulse duration can influence residual thermal damage and wound healing. Our study us...
Read MoreRandomized, Double-Blind, Split-Face Study Evaluating Fractional Ablative Erbium:YAG Laser-Mediated Trans-Epidermal Delivery of Cosmetic Actives and a Novel Acoustic Pressure Wave Ultrasound Technology for the Treatment of Skin Aging, Melasma, and Acne Scars
November 2015 | Volume 14 | Issue 11 | Original Article | 1191 | Copyright © November 2015
BACKGROUND: Fractional laser resurfacing enhances trans-epidermal delivery (TED), however laser penetration depths >250- μm fail to substantively increase drug delivery.
AIM: Evaluate the s...
Read MoreClinical Trial Review
September 2015 | Volume 14 | Issue 9 | Features | 1074 | Copyright © September 2015
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreAzelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application
September 2015 | Volume 14 | Issue 9 | Original Article | 964 | Copyright © September 2015
Azelaic acid is a complex molecule with many diverse activities. The latter include anti-infective and anti-inflammat...
Read MoreMinocycline Pigmentation Following Carbon Dioxide Laser Resurfacing: Treatment With the Q-switched Nd:YAG Laser
April 2015 | Volume 14 | Issue 4 | Case Reports | 411 | Copyright © April 2015
Minocycline is among the most common drugs to cause drug-induced pigmentation. Dermal deposition of drug metabolites typically occurs in areas of vascular leakage, such as surrounding lower extremity ...
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