Found 199 articles for: "chemotherapy"
Ingenol Mebutate: Expanded Utility
February 2020 | Volume 19 | Issue 2 | Original Article | 156 | Copyright © February 2020
Ingenol mebutate (IM) is a novel drug that was developed for the treatment of actinic keratosis (AK). The drug works by a dual mechanism of action -- a rapid induction of cell death by necrosis along ...
Read MoreCombination Topical Chemotherapy for the Treatment of an Invasive Cutaneous Squamous Cell Carcinoma
February 2020 | Volume 19 | Issue 2 | Case Reports | 202 | Copyright © February 2020
INTRODUCTION: Standard of care for squamous cell carcinoma (SCC) is usually surgical, with either excision or Mohs micrographic surgery. However, surgery may not be ideal for elderly patients with num...
Read MoreBeta-Blockers for Pyogenic Granuloma: A Systematic Review of Case Reports, Case Series, and Clinical Trials
October 2019 | Volume 18 | Issue 10 | Original Article | 1006 | Copyright © October 2019
Pyogenic granuloma (PG) is an acquired vascular growth on the skin and mucous membranes. Even though PG is a benign tumor, treatment is required due to associated risk of ulceration and bleeding, cosm...
Read MoreImpact of Gene Expression Profile Testing on the Management of Squamous Cell Carcinoma by Dermatologists
October 2019 | Volume 18 | Issue 10 | Original Article | 980 | Copyright © October 2019
Background: The incidence of cutaneous squamous cell carcinoma (cSCC) is increasing likely due to improved detection and a growing elderly population. Although the prognosis of cSCC i...
Read MoreInvention in Dermatology: A Review
September 2019 | Volume 18 | Issue 9 | Original Article | 904 | Copyright © September 2019
Dermatologists are among the most inventive physicians, trained in the multiple disciplines of medical dermatology, surgical dermatology, and dermatopathology. Many of the advances in de...
Read MoreTreatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature
July 2019 | Volume 18 | Issue 7 | Case Reports | 693 | Copyright © July 2019
Keratoacathoma (KA) is a unique clinical pathological entity that is difficult to categorize. Differentiating a KA from a squamous cell carcinoma (SCC) is important for treatment implica...
Read MoreTopical Ozenoxacin Cream 1% for Impetigo: A Review
July 2019 | Volume 18 | Issue 7 | Original Article | 655 | Copyright © July 2019
Background: Impetigo, a bacterial infection that is highly contagious, involves the superficial skin. Topical treatment for impetigo includes amongst other bacitracin, g...
Read MoreTreating Acne With Topical Antibiotics: Current Obstacles and the Introduction of Topical Minocycline as a New Treatment Option
March 2019 | Volume 18 | Issue 3 | Original Article | 240 | Copyright © March 2019
Oral antibiotics are well established treatments for acne vulgaris but are associated with undesirable side effects. Topical antibiotics offer an improved safety profile but have led to an alarming ri...
Read MoreBullous Pemphigoid Associated With a New Combination Checkpoint Inhibitor Immunotherapy
January 2019 | Volume 18 | Issue 1 | Case Reports | 103 | Copyright © January 2019
hospiNovel immunotherapies including antibodies to programmed death ligand 1 (PD-1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) have become common therapies for neoplasms including metas...
Read MoreRapidly Enlarging Malignant Proliferating Trichilemmal Tumor in a Young Female
December 2018 | Volume 17 | Issue 12 | Case Reports | 1325 | Copyright © December 2018
Malignant proliferating trichilemmal tumors are rare adnexal neoplasms that most commonly occur on the scalp in elderly women. These tumors are associated with recurrence and even nodal or distant met...
Read MoreSenior Resident Peer-to-Peer Case StudiesAfter
November 2018 | Volume 17 | Issue 11 | Editorials | 1248 | Copyright © November 2018
The content of these case studies, ideal to review during peer study groups, was developed by Elizabeth Robinson, MD and Jennifer Aronica, MD under the guidance of dermatologist Adam Friedman, MD, FAA...
Read MoreIntralesional 5-Fluorouracil in the Treatment of Lower Leg Squamous Cell Carcinoma
November 2018 | Volume 17 | Issue 11 | Features | 1241 | Copyright © November 2018
Non-melanoma skin cancer (NMSC) is the most commonly diagnosed cancer in the United States.1,2 There are ...
Read MoreSafety and Efficacy of a Once-Daily Halobetasol Propionate 0.01% Lotion in the Treatment of Moderate-to-Severe Plaque Psoriasis: Results of Two Phase 3 Randomized Controlled Trials
October 2018 | Volume 17 | Issue 10 | Original Article | 1062 | Copyright © October 2018
BACKGROUND: Topical corticosteroids (TCS) are the mainstay of psoriasis treatment; long-term safety concerns limiting con...
Read MoreTopical Antibacterial Agent for Treatment of Adult and Pediatric Patients With Impetigo: Pooled Analysis of Phase 3 Clinical Trials
October 2018 | Volume 17 | Issue 10 | Original Article | 1051 | Copyright © October 2018
Ozenoxacin is a novel topical antibacterial agent with potent bactericidal activity against Gram-positive bacteria that has been developed as a 1% cream for treatment of impetigo. This article present...
Read MoreThe Evaluation of Cutaneous Metastasis from an Unknown Primary
July 2018 | Volume 17 | Issue 7 | Case Reports | 804 | Copyright © July 2018
We present the case of a man that had a rapidly growing nodule on his face. Removal of the lesion was more difficult than anticipated because it was tightly adherent to adjacent tissue. Pathology from...
Read MoreWidespread Skin Necrosis Secondary to Gemcitabine Therapy
May 2018 | Volume 17 | Issue 5 | Case Reports | 582 | Copyright © May 2018
Gemcitabine, a pyrimidine nucleoside analogue, is an oncologic agent used in the treatment of cutaneous T-cell lymphoma (CTCL). Common dermatologic reactions associated with gemcitabine include alopec...
Read MoreSuccessful Therapy of Severe Oro-Labial Herpes Simplex With Muco-Adhesive Acyclovir
April 2018 | Volume 17 | Issue 4 | Case Reports | 479 | Copyright © April 2018
Although muco-adhesive acyclovir 50mg tablets are only approved for the management of recurrent oro-labial HSV-1 infections, their ability to achieve extremely high concentrations in saliva and oral t...
Read MoreDihydroxyacetone: A Review
April 2018 | Volume 17 | Issue 4 | Original Article | 387 | Copyright © April 2018
The sunless tanning industry has experienced rapid growth due to public education on the dangers of ultraviolet radiation on skin and improvements in products. Dihydroxyacetone (DHA) is a 3-carbon sug...
Read MoreLocally Advanced Basal Cell Carcinoma: Two Severe Case Presentations and Review
March 2018 | Volume 17 | Issue 3 | Case Reports | 358 | Copyright © March 2018
Basal cell carcinoma (BCC) is a common skin malignancy comprising 80% of non-melanoma skin cancers.1 Over 2.8 million cases are estimated to be diagnosed in the United States alone each year. Advanced...
Read MoreDupilumab in the Treatment of Dyshidrosis: A Report of Two Cases of Dyshidrotic Eczema
March 2018 | Volume 17 | Issue 3 | Case Reports | 355 | Copyright © March 2018
Dyshidrotic eczema is a distinct entity, often considered on the spectrum of atopic dermatitis, that primarily effec...
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