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New hope for treating shingles patients -- a study published in the Journal of Drugs in Dermatology

NEW YORK, March 5, 2015 /PRNewswire/ -- The Journal of Drugs in Dermatology is delighted to present new findings from the Mayo Clinic's Department of Dermatology showing possible relief from the complications and pain secondary to Herpes Zoster, commonly known as shingles.

The pain associated with shingles is difficult to treat; and there have been few studies addressing the question of medical treatment of postherpetic pruritus. However, in "Amitriptyline/Ketamine as Therapy for Neuropathic Pruritus and Pain Secondary to Herpes Zoster," John R. Griffin MD and Mark D.P. Davis MD show that some reduction of both the pruritus and the pain was achieved with the usual multimodal therapy and the addition of topical 2% amitriptyline/0.5% ketamine gel. In this case study, a patient with severe problems unresponsive to standard medical therapy was able to be dismissed from in-patient care. This could be great news for patients suffering from shingles worldwide.

Quote from the authors:
'The patient's average pruritus score decreased from 7/10 to 5/10, with intermittent exacerbations, within 4 days of initiating topical amitriptyline/ketamine therapy while keeping all other interventions at previous doses. His pain levels showed a similar response. The patient stated that the addition of this medication gave him "significant" relief.'

Please find the article here.

About the Journal of Drugs in Dermatology

A product of SanovaWorks, the Journal of Drugs in Dermatology (JDD) is a full-color, peer-reviewed publication indexed with MEDLINE®/PubMed®. Founded by the renowned Dr. Perry Robins MD and now in its 12th year, JDD presents original articles, award-winning case reports, and timely features pertaining to new methods, techniques, and drug therapy in dermatology. Articles are reviewed by an International Editorial Board of over 150 renowned experts, led by Editor-in-Chief Dr. Perry Robins MD and Co-Editor-in-Chief Deborah S. Sarnoff MD. The journal offers one of the swiftest routes to disseminating information to thousands of dermatologists, both in the United States and internationally. JDD has also been recognized as the official publication of the International Society of Dermatologic Surgery (ISDS) and the Orlando Dermatology Aesthetic and Clinical (ODAC) Conference. Visit for article archives, access to CME activities, supplements, and author instructions. For more information, visit and

Journal of Drugs in Dermatology


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