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Cardiac catheterization is a very common procedure carried out for diagnostic as well as therapeutic reasons. Complications are not surprising due to the invasive nature of the procedure. Most of these complications have been seen numerous times by cardiologists who frequent the catheterization laboratory. Unfortunately, this patient experienced an extremely rare complication that ultimately resulted in his death. Here, the authors report a case of toxic epidermal necrolysis (TEN) resulting from the nonionic radiocontrast agent used in cardiac catheterization.

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