JDDonline.com

March 2010

273

VOLUME 9 • ISSUE 3

Generalized Necrobiotic Xanthogranuloma Successfully Treated With Lenalidomide

Abstract

Necrobiotic xanthogranuloma (NXG) presents a therapeutic challenge to clinicians. Generalized NXG has limited treatment options. A patient presented to the authors with generalized NXG associated with monoclonal gammopathy of unknown significance (MGUS), a plasma cell dyscrasia considered to be a precursor to multiple myeloma.

The patient was treated with lenalidomide, a derivative of thalidomide with efficacy in treatment of multiple myeloma. Resolution of paraproteinemia was associated with resolution of NXG.

Download PDF One Time Purchase

In proceeding with payment you agree to purchase a one-time PDF download of the selected JDDonline content. The PDF is only available for single computer on-screen use; printing, duplicating, or reproducing this content is strictly prohibited per the Copyright Protection Act.