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Title: Generalized Necrobiotic Xanthogranuloma Successfully Treated With Lenalidomide
Author: Sirunya Silapunt MD and Susan Y. Chon MD
Abstract: Necrobiotic xanthogranuloma (NXG) presents a therapeutic challenge to clinicians. Generalized NXG has limited treatment options. A patient presented to the authors with generalized NXG associated with monoclonal gammopathy of unknown significance (MGUS), a plasma cell dyscrasia considered to be a precursor to multiple myeloma.

The patient was treated with lenalidomide, a derivative of thalidomide with efficacy in treatment of multiple myeloma. Resolution of paraproteinemia was associated with resolution of NXG.
Section: Case Report
Year: 2010
Volume: 9
Issue: 3
Page: 273
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