Kimberly J. Butterwick, MD
Submental liposuction is an excellent procedure for improving the aging neck by reducing the cervicomental
angle and increasing the definition of the mandibular border. However, it does not address the loss of volume
of the chin and perioral areas caused by atrophy of hard and soft tissues.
In this study, thirty patients underwent concomitant submental tumescent liposuction and fat augmentation
with the FAMI (fat autograft muscle injection) technique in order to assess short-term results and complications
associated with these two relatively noninvasive procedures.
All patients had improvement in the cervicomental border, a smoother mandibular border, and a more proportioned
chin following 3-5 days of swelling. Patients followed for 6 months to one year had long term retention
of fat. There were no significant complications.
In this preliminary series, submental tumescent liposuction with FAMI provided enhanced aesthetic results
with little downtime and minimal complications
David J. Narins, MD and Rhoda S. Narvins, MD
There has been considerable interest in using non-ablative methods to rejuvenate the skin. The ThermaCool
TC™ (Thermage® Inc.) is a radiofrequency (RF) device that has been introduced to induce tightening of the
address the problem of skin via a uniform volumetric heating into the deep dermis tightening, resulting in a
‘non-surgical facelift’. Radiofrequency produces a uniform volumetric heating into the deep dermis. Twenty
treatment areas in 17 patients were treated to evaluate the efficacy and safety of RF treatment to the brow and
jowls. The technique was found to produce gradual tightening in most patients, and there were no adverse
Tina S. Alster, MD and Elizabeth L. Tanzi, MD
Successful and long-standing eradication of sebaceous hyperplasia has remained difficult due to the propensity
of these lesions to be extensive. Current treatments include excision, electrodesiccation, laser vaporization,
and oral isotretinoin, each often associated with unacceptable side effects or lesional recurrence. The purpose
of this study was to evaluate the safety and effectiveness of laser-assisted photodynamic therapy using topical
5-aminolevulinic acid (5-ALA) and 595 nm pulsed dye laser (PDL) irradiation for the treatment of sebaceous
Ten patients with sebaceous hyperplasia received 1 or 2 treatments at 6 week intervals with topical 20% 5-ALA
followed 1 hour later by 595 nm PDL irradiation. Matched lesions served as controls and were either treated
with PDL alone or were left untreated. Patients were evaluated at regular intervals for 3 months.
Results demonstrated that combination topical 5-ALA and PDL treatment effected better clinical results than
PDL treatment alone. No changes were observed in untreated control lesions. Side effects were mild and limited
to transient erythema, edema, and focal crusting.
It is the conclusion of the authors that laser-assisted photodynamic therapy with topical 5-ALA and PDL irradiation
can achieve safe and effective improvement of sebaceous hyperplasia. Further study is warranted to
determine the longevity of the clinical results observed.
Fat transfer is most effective when fresh fat is used, with excess fat frozen and saved for touch-ups. The obvious
benefit to using frozen fat is that harvesting does not have to be done each time fat is injected. It is important
to be able to easily store the fat in a freezer and be confident that it will not harbor bacterial growth. We
studied frozen fat from 10 patients after 12 months and 10 patients after 24 months for sterility. Cultures were
negative for all specimens, showing that frozen fat is safe to use and should not cause infection.
Doris Hexsel, MD; Marcio Serra, MD; Rosemari Mazzuco, MD; Taciana Dal'Forno, MD and Debora Zechmeister, RPh
Phosphatidylcholine was initially used in emergencies and in the treatment of atheroma plaques in cardiac diseases.
Recently, it has also been used in the treatment of localized fat deposits. We report on the authors’ clinical
experience of the use of 250 mg/ml phosphatidylcholine injections in the treatment of subcutaneous fat
deposits, showing the clinical response and side-effects. Volunteers received phosphatidylcholine injections in
several areas of localized fat deposits, with a minimum interval of one week and mean interval of 15 days
between applications. Laboratory tests were performed during the period of the drug use. Clinical results
reflect that phosphatidylcholine was efficacious in reducing the fatty pads in the treated areas, with few side
effects. From the authors’ point of view, the off-label use of phosphatidylcholine in the treatment of fatty pads
and small areas of localized fat is safe, low cost, and effective.
Lewis P. Stolman, MD, FACP, FRCP©
Hyperhidrosis, or excessive sweating, is a disorder that may cause social isolation or occupational disability. It
may be generalized or localized, and although frequently idiopathic it may be a manifestation of a number of
important systemic diseases. Drugs, surgical procedures, and electrical devices may all be employed by the
physician as therapeutic weapons to treat hyperhidrosis.
Neil S. Sadick, MD, FACP, FAACS
Cosmeceutical skin care products, which fall somewhere between cosmetics and pharmaceuticals, are playing an increasing role in the dermatologist's daily practice1-9. These agents contain active ingredients with known and documented biologic effects on the skin. Cosmeceutical sales represent the greatest growth segment of the skin-care market10-11. Although many of these agents have previously been marketed in drug stores, department stores, and pharmacies, these agents are now commonly being dispensed by dermatologists in their office settings. There is therefore a growing strategic alliance between the dermatology community and the cosmetic industry, which is in a process of evolution1-4.
The major challenge facing the practicing dermatologist is how to employ this ever-growing array of products to improve patient care. Many questions are still unanswered, and the ultimate recommendation of which are optional products for the aging patient should be based upon peer-reviewed, scientifically based clinical research studies which prove the agent's therapeutic efficacy.
From Sun & Skin News, Vol. 20, No.2
No abstract details for the moment.